BioSAXS

Institution: IC

Departement: DSCTM

Typology: Facility

Location: IC-CNR, Via G. Amendola 122/O 70126 Bari

Contacts:

• Cinzia Giannini (cinzia.giannini@cnr.it)
• Francesco Scattarella (francesco.scattarella@cnr.it)

Description:

BioSAXS will allow to conduct preliminary studies, select the best samples to be analyzed (possibly) in synchrotron light laboratories. Furthermore, if equipped with Size Exclusion Cromathograhy (SEC-BioSAXS) and Ultra Small Angle Scattering (USAXS), it will be possible to study macromolecules, selected by size, up to 1 micron. Finally, a reactivity chamber will allow to manage samples in an inert or controlled atmosphere, avoiding exposure of the substances to oxygen during handling. XENOCS XEUSS3.0 system, HR model, equipped with a motorized dual source: Ga Excillum liquid jet source and Cu micro-source. Detector: Eiger 2R (1M), moving in vacuum from 42.5 mm to 1800 mm (sample-to-detector distance) Bonse-Hart 4-bounce Si(111) channel cut crystals monochromator and analyzer for uSAXS. Biocube system. Size-exclusion chromatography is coupled with SAXS (SEC-SAXS) using an AKTA goTM protein purification system.

Team:

https://www.ic.cnr.it/laboratorio/biosaxs/

XENOCS-XEUSS3.0 system, HR model